The Transhumanist Wager is a science fiction novel written by Zoltan Istvan. It follows the story of Jethro Knights, a transhumanist who becomes a political and philosophical leader in a world on the brink of a technological revolution. The novel explores themes of radical life extension, human enhancement, and the clash between transhumanist ideals and societal norms. The Transhumanist Wager presents a provocative vision of a future shaped by transhumanist principles.