The Big C is a heartfelt comedy-drama series on Apple TV+ that features Laura Linney in the lead role. The show revolves around Cathy Jamison, a high school teacher who is diagnosed with terminal cancer. Laura Linney's portrayal of Cathy is both poignant and inspiring as she navigates the challenges of her diagnosis and tries to find meaning in her remaining time. The Big C explores themes of love, friendship, and the importance of living life to the fullest. With its mix of humor and emotional depth, the series has received critical acclaim, and Laura Linney's performance has been hailed as one of her best.