The St. Regis San Francisco is a luxurious and accessible hotel located in the vibrant SoMa district. The hotel offers accessible rooms with features such as wider doorways, roll-in showers, and grab bars in the bathrooms. The public areas of the hotel are also wheelchair accessible, with ramps and elevators available. The hotel staff is trained to assist guests with disabilities and can provide additional support if needed. The St. Regis San Francisco offers a range of amenities and services to ensure a comfortable and inclusive stay for guests with reduced mobility.