Dedicate your second day to exploring the Vatican Museums and the famous Sistine Chapel. The Vatican Museums house an extensive collection of art and historical artifacts, including works by renowned artists such as Michelangelo, Raphael, and Leonardo da Vinci. Marvel at the intricate details of the Sistine Chapel's ceiling, painted by Michelangelo, and admire the masterpieces displayed throughout the museums. Take your time to fully appreciate the rich cultural heritage within these walls.