The Residence Inn San Diego Downtown is a pet-friendly hotel that provides accessible accommodations for guests with reduced mobility. The hotel offers accessible rooms with features like roll-in showers, grab bars, and lowered sinks. The public areas are wheelchair accessible, and there are ramps and elevators throughout the property. Guests can enjoy amenities such as a fitness center, outdoor pool, and accessible dining options. The hotel's central location allows easy access to popular attractions, shopping, and dining destinations in San Diego.