Dedicate your second day in Spoleto to exploring its rich art and culture. Start with a visit to the Museo Archeologico Nazionale, where you can learn about the ancient history of the region. Then, head to the Teatro Romano, an ancient Roman theater that still hosts performances today. In the afternoon, visit the Galleria d'Arte Moderna, which houses a collection of contemporary art. Don't miss the opportunity to attend a classical music concert at the famous Festival dei Due Mondi, if it's taking place during your visit.
