The Power of a Positive No, authored by William Ury, focuses on the art of saying 'no' effectively while maintaining positive relationships. The book provides a framework for delivering a firm and respectful 'no' that protects one's interests without damaging the relationship. It emphasizes the importance of setting boundaries, understanding underlying interests, and finding creative solutions. The Power of a Positive No offers valuable insights and practical techniques for business professionals who often face challenging situations where saying 'no' is necessary.